This study investigates factors affecting tourism demands in Selected OIC COUNTRIES for the period of 2004 to 2016. The economic variables used in this study are tourist receipts, GDP per capita, real exchange rate, population, Trade openness and Consumer Price Index. GLS method is applied in the research model in order to investigate the relationship between tourist receipts, GDP per capita, real exchange rate, population, Trade openness and Consumer Price Index. In this research, we find that GDP per capita, real exchange rate, population, Trade openness have a Positive impact on tourist receipts. These factors play a crucial role in tourism demand. The adoption of appropriate economic policies, in line with the tourism development policies, such as the appropriate rate of exchange, can help to reduce the travel costs and it enhances the competitive advantage of this industry. The results also showed that the Consumer price index (CPI) variable has a positive impact and almost equal to zero but it is insignificant in explaining tourism demand.